Biomarkers and Pharmacodynamics

Biomarkers and Pharmacodynamics

Scinovo’s Simoa, FACS and MSD platforms support nonclinical and clinical pharmacodynamic evaluation and biomarker/receptor occupancy bioanalysis. We focus on selection and validation specific cytokines and biomarkers from a large number of candidates in large scale clinical trials. The results could offer evidence for PK/PD correlation study, dosage selection and safety window confirmation. 

·Biomarkers: Souble or cellular biomarker
·Receptor occupancy (RO): Antibody, fusion protein and small molecular target drugs
·Target interaction in vivo : Immunophenotyping or phosphorylation etc.